Yorba Linda, CA November 28, 2017
Androgen receptor (AR) signaling remains a driver in the lethal phenotype of prostate cancer, castrate resistant prostate cancer (CRPC). Novel second generation enhanced androgen inhibitors, abiraterone acetate and enzalutamide, improve survival of CRPC patients following androgen deprivation therapy.
However, a significant group of patients demonstrate primary resistance to these agents and other patients acquire resistance during therapy. The mechanisms of enhanced androgen inhibitor resistance are complex. AR-dependent mechanisms involve AR overexpression, AR mutation, intra-tumor ligand biosynthesis, modulation of co-activators and co-repressors and expression of AR spice variants.
Sponsored by Agilent this webinar will provide participants with a better understanding of metastatic prostate cancer as a phenotypically diverse disease. They will also learn about the analytical instrumentation being used in diagnostic and predictive marker development.
The speaker for this event will be Dr. Mark Titus, an associate professor in the Department of Genitourinary Medical Oncology at the MD Anderson Cancer Center.
Titus earned his doctorate degree from the University of Washington, before moving on to complete his postdoctoral research in the Laboratories for Reproductive Biology, University of North Carolina School of Medicine at Chapel Hill. His initial faculty appointment was in the Department of Urology at Roswell Park Cancer Center, Buffalo NY. He later joined the faculty in Genitourinary Medical Oncology at MD Anderson Cancer Center.
LabRoots will host the webinar December 5th, 2017, at 6:00 a.m. PST. To learn more this event and the continuing education credits, or to register for free, click here.
For Research Use Only. Not for use in diagnostic procedures.
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