LabRoots Presents Educational Webinar Exploring Androgen Signaling in Advanced Prostate Cancer Models


Mark Titus, PhD Associate Professor, Department of Genitourinary Medical Oncology

Yorba Linda, CA

Androgen receptor (AR) signaling remains a driver in the lethal phenotype of prostate cancer, castrate resistant prostate cancer (CRPC). Novel second generation enhanced androgen inhibitors, abiraterone acetate and enzalutamide, improve survival of CRPC patients following androgen deprivation therapy.

However, a significant group of patients demonstrate primary resistance to these agents and other patients acquire resistance during therapy. The mechanisms of enhanced androgen inhibitor resistance are complex. AR-dependent mechanisms involve AR overexpression, AR mutation, intra-tumor ligand biosynthesis, modulation of co-activators and co-repressors and expression of AR spice variants.

Sponsored by Agilent this webinar will provide participants with a better understanding of metastatic prostate cancer as a phenotypically diverse disease. They will also learn about the analytical instrumentation being used in diagnostic and predictive marker development.

The speaker for this event will be Dr. Mark Titus, an associate professor in the Department of Genitourinary Medical Oncology at the MD Anderson Cancer Center.

Titus earned his doctorate degree from the University of Washington, before moving on to complete his postdoctoral research in the Laboratories for Reproductive Biology, University of North Carolina School of Medicine at Chapel Hill. His initial faculty appointment was in the Department of Urology at Roswell Park Cancer Center, Buffalo NY. He later joined the faculty in Genitourinary Medical Oncology at MD Anderson Cancer Center.

LabRoots will host the webinar December 5th, 2017, at 6:00 a.m. PST. To learn more this event and the continuing education credits, or to register for free, click here.

For Research Use Only. Not for use in diagnostic procedures.

About LabRoots
LabRoots is the leading scientific social networking website, which provides daily scientific trending news and science-themed apparel, as well as produces educational virtual events and webinars, on the latest discoveries and advancements in science. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

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